Guangmai Technology is professional in making the UV-B Ultraviolet 300nm 310nm 320nm LED Chip SMT Type.
Mr. Yin Dakui, former Vice Minister of the Ministry of Health and Honorary President of the Chinese Medical Doctor Association, said at the launching ceremony of the "National Dermatology Rescue Project in China" Shanghai Station that as of 2014, about 420 million people worldwide suffer from skin diseases. , China has nearly 150 million people[5]. Among them, the most common skin diseases are psoriasis (psoriasis), vitiligo, atopic dermatitis, etc. These diseases are characterized by a slow healing process, stubbornness and repetition, and the healing phase requires a lot of energy, manpower and material resources. According to the survey results of the "Dermatological Quality of Life Scale", in addition to the pain and itching, it is normal for patients with skin diseases to reduce their quality of social life because they affect their appearance.
Vitiligo is an autoimmune disease in which melanin cannot be secreted normally due to the reduction or lack of melanocytes. The skin lesions are milky white pigmented spots. The disease mechanism is not yet clear, and most scholars believe that autoimmune factors play an important role in the pathogenesis of vitiligo [6]. From the perspective of cell biology, regulatory T cells in patients can not only destroy the immunomodulatory effect of melanocytes, but also activate cytotoxic T cells by their lack of function. Cytotoxic T cells recognize and fight against melanocytes. Antigens eventually destroy melanocytes [7-8].
UVB treatment of vitiligo by inhibiting or promoting related cytokines, while inducing cytotoxic T cell apoptosis and inhibiting the release of pro-inflammatory factors. Scientists such as Imokawa G [10] found that the expression of Endothelin-1, Interleukin-1α, and Tyrosinase secreted by keratinocytes increased after UVB irradiation. ET-1 is the mitogen of melanocytes, and the increase of its content promotes the division, proliferation and migration of the remaining melanocytes. The role of tyrosinase is to catalyze the formation of melanin in melanocytes. In addition, Yang Xianlu et al. [11] found that UVB can inhibit the expression of IL-17 and IL-23. IL-17 is a cytokine induced by Th17 cells to induce differentiation and has a pro-inflammatory effect, while IL-23 indirectly promotes inflammation by up-regulating the secretion of pro-inflammatory factors TNF-α, IL-1β and IL-17. Therefore, UVB regulates the immune balance between regulatory T cells and Th17 cells by inhibiting the release of IL-6, IL-17, IL-23, IL-1β, TNF-α and other inflammatory cytokines, thereby effectively suppressing the immune response .
In the past few years, the UVB LEDs that can be used in the market are basically monopolized by Japanese and Korean companies, and the country is in its infancy. Based on the excellent performance of Guangmai Tech UVC LED, Sanan Optoelectronics has newly launched UVB chips with a wavelength range of 308-320 nm, as well as high-performance packages that can meet the different design requirements of customers. GMKJ LED UVB chip sizes include 20 mil, 30 mil and 42 mil to choose from. A single chip can reach 40 mW of optical power under 350mA current drive.
Parameter | Symbol | Conditions | Min | Avg. | Max | Units |
Forward Voltage | VF | IF=150mA | 5.00 | -- | 8.00 | V |
Thermal Resistance Junction To Board | RΘJ-B | IF=150mA | -- | 8 | -- | °C/W |
Radiant Flux | Φe | IF=150mA | 20 | 30 | mW | |
Peak wavelength | λp | IF=150mA | 305 | 315 | nm | |
Temperature Coefficient of Forward Voltage | ∆VF/∆T | IF=150mA | −− | -2 | −− | mV/°C |
Reverse Current | IR | VR=5V | −− | −− | 10 | μ A |
Viewing Angle [1] | 2Θ1/2 | IF=150mA | −− | 120 | −− | Deg |
About Guangmai
Shenzhen Guangmai Technology Co., Ltd. was established in 2006, focusing on high-end LED packaging, a national high-tech enterprise. Mainly develop and produce two series of products, healthy light source and smart light source. Healthy light source series include: UVA LED, UVB LED, UVC LED, mainly used in light curing, phototherapy, sterilization and other markets; smart light source series: IR LED, VCSEL, etc., mainly used in security, biometrics, 3D sensing, laser Radar, driving monitoring, digital medical, AR/VR, optical communications and other markets. Based on its own LED packaging advantages, the company has created a series of products with patent protection and high brand added value. Welcome to contact us to discuss cooperation matters.
Datasheet:
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You can download the datasheet of UV-B Ultraviolet 300nm 310nm 320nm LED Chip SMT Type from the head of this page.
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